Custom RNA 50 is perfect for designing short guide RNAs for nucleases that don’t require long sequences, such as Cpf1. You can use it to design your own Cas9 crRNA and custom 3′ linker to a tracrRNA.

Custom RNA 75 is perfect for designing guide RNAs for nucleases that don’t require guides as long as S. pyogenes Cas9. You can use it to design your own Cas9 tracrRNA and custom 5′ linker to a crRNA.

Custom RNA 100 is perfect for designing full length sgRNA for CRISPR at a practical scale and price point. You can custom design your entire sgRNA sequence from 76-103 nucleotides.

• Custom RNA Specifications
• Product Type: Fully Synthetic RNA for CRISPR or other applications
• Purification: High-Quality Liquid Chromatography SPE
• Analysis Method: Electrospray Ionization Mass Spectrometry
• Shipping Format: Nuclease-free Tubes

Working with stem cells or other difficult targets? Try Chemically Modified Synthetic RNA.

Chemically modified sequences can provide additional RNA stability with improvements in editing efficiency for particular cell types (e.g. stem cells, K562, prokaryotic) and genomic targets that prove otherwise challenging to edit. For a chemically modified version of our synthetic RNA, we offer 2’-O-methyl analogs and 3’ phosphorothioate internucleotide linkages at the first three 5’ and 3’ terminal RNA residues. 

Advanced RNA 100

• Your 76-103nt Sequence
• Material for 10-20 Transfections
• Quantity: 3 nmol by OD260
• Modified RNA Optional*
• Ships in 5-10 Business Days
   

Advanced RNA 75

• Your 51-75nt Sequence
• Material for 25-50 Transfections
• Quantity: 5 nmol by OD260
• Modified RNA Optional*
• Ships in 5-10 Business Days 

Advanced RNA 50

• Your 20-50nt Sequence
• Material for 25-50 Transfections
• Quantity: 5 nmol by OD260
• Modified RNA Optional*
• Ships in 5-10 Business Days